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A defense of syntax-based gene concepts in postgenomics: ‘Genes as modular subroutines in the master genomic program’

Baetu, Tudor (2010) A defense of syntax-based gene concepts in postgenomics: ‘Genes as modular subroutines in the master genomic program’. In: [2010] Philosophy of Science Assoc. 22nd Biennial Mtg (Montréal, QC) > PSA 2010 Contributed Papers.

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    Abstract

    The purpose of this article is to update and defend syntax-based (conserved DNA-sequence motifs) gene concepts. I show how syntax-based concepts can and have been extended to accommodate complex cases of processing and gene expression regulation. In response to difficult cases and causal parity objections, I argue that a syntax-based approach fleshes out a deflationary concept defining genes as genomic sequences and organizational features of the genome contributing to a phenotype. These organizational features are an important part of accepted molecular explanations, provide the theoretical basis for a large number of experimental techniques and practical applications, and play a crucial role in in annotating the genome, deriving predictions and constructing bioinformatics models.


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    Item Type: Conference or Workshop Item (UNSPECIFIED)
    Keywords: Philosophy of biology, concepts of the gene, bioinformatics
    Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
    Conferences and Volumes: [2010] Philosophy of Science Assoc. 22nd Biennial Mtg (Montréal, QC) > PSA 2010 Contributed Papers
    Depositing User: Tudor Baetu
    Date Deposited: 04 Nov 2010 12:41
    Last Modified: 04 Nov 2010 12:41
    Item ID: 8373
    URI: http://philsci-archive.pitt.edu/id/eprint/8373

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