PhilSci Archive

Synthetic Modeling and the Functional Role of Noise

Knuuttila, Tarja and Loettgers, Andrea (2011) Synthetic Modeling and the Functional Role of Noise. In: [2011] Epistemology of Modeling & Simulation: Building Research Bridges between the Philosophical and Modeling Communities (Pittsburgh; 1-3 April 2011).

[img]
Preview
PDF
Download (725Kb) | Preview

    Abstract

    In synthetic biology the use of engineering metaphors to describe biological organisms and their behavior has become a common practice. The concept of noise provides one of the most compelling examples of such transfer. But this notion is also confusing: While in engineering noise is a destructive force perturbing artificial systems, in synthetic biology it has acquired an additional functional meaning. It has been found out that noise is an important factor in driving biological processes such as gene regulation, development, and evolution. How did noise acquire this dual meaning in the field of synthetic biology? In this paper we study the emergence of the functional meaning of noise in relation to synthetic modeling. We will pay particular attention to the interdisciplinary aspects of this process highlighting the way borrowed concepts, analogical reasoning and the use of cross-disciplinary computational templates were entwined in it.


    Export/Citation:EndNote | BibTeX | Dublin Core | ASCII/Text Citation (Chicago) | HTML Citation | OpenURL
    Social Networking:

    Item Type: Conference or Workshop Item (UNSPECIFIED)
    Keywords: Models, Synthetic biology, Analogies, Computational templates, Noise, Interdisciplinarity, Scientific concepts, Engineering
    Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
    General Issues > Models and Idealization
    Conferences and Volumes: [2011] Epistemology of Modeling & Simulation: Building Research Bridges between the Philosophical and Modeling Communities (Pittsburgh; 1-3 April 2011)
    Depositing User: Tarja Tellervo Knuuttila
    Date Deposited: 27 Mar 2011 00:27
    Last Modified: 27 Mar 2011 00:27
    Item ID: 8532
    URI: http://philsci-archive.pitt.edu/id/eprint/8532

    Actions (login required)

    View Item

    Document Downloads