Fagan, Melinda B. (2012) The stem cell uncertainty principle. In:  Philosophy of Science Assoc. 23rd Biennial Mtg (San Diego, CA) > PSA 2012 Contributed Papers.
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Stem cells are defined by capacities for both self-renewal and differentiation. Many different entities satisfy this working definition. Explicating the stem cell concept reveals it to be relational and relative, requiring contextualization by a cell lineage, organismal source, cell environments, and traits of interest. Not only are stem cell capacities relative to an experimental context; the stem cell concept imposes evidential constraints on the interpretation of experimental results. In consequence, claims about stem cell capacities are inherently uncertain. I discuss the implications of this result for progress in stem cell research and its public understanding.
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|Item Type:||Conference or Workshop Item (UNSPECIFIED)|
|Keywords:||Experiment, Models, Stem cells, Technology, Uncertainty|
|Subjects:||Specific Sciences > Biology > Developmental Biology|
Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Experimentation
|Conferences and Volumes:|| Philosophy of Science Assoc. 23rd Biennial Mtg (San Diego, CA) > PSA 2012 Contributed Papers|
|Depositing User:||Melinda Fagan|
|Date Deposited:||02 Jul 2012 12:23|
|Last Modified:||02 Jul 2012 12:23|
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