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Synthetic Modeling and Mechanistic Account: Material Recombination and Beyond

Knuuttila, Tarja and Loettgers, Andrea (2012) Synthetic Modeling and Mechanistic Account: Material Recombination and Beyond. In: [2012] Philosophy of Science Assoc. 23rd Biennial Mtg (San Diego, CA) > PSA 2012 Contributed Papers.

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    Abstract

    Recently, Bechtel and Abrahamsen have argued that mathematical models study the dynamics of mechanisms by recomposing the components and their operations into an appropriately organized system. We will study this claim through the practice of combinational modeling in circadian clock research. In combinational modeling experiments on model organisms and mathematical/computational models are combined with a new type of model—a synthetic model. While we appreciate Bechtel and Abrahamsen’s point that mathematical/computational models are used to provide dynamic mechanistic explanations, we think that the strategy of recomposition is more complicated than what Bechtel and Abrahamsen indicate. Moreover, as we will show, synthetic modeling as a kind of material recomposition strategy also points beyond the mechanistic paradigm.


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    Item Type: Conference or Workshop Item (UNSPECIFIED)
    Keywords: Dynamic mechanistic explanations, mathematical models, synthetic models, genetic circuits, noise, modularity, integration
    Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
    General Issues > Experimentation
    General Issues > Explanation
    General Issues > Models and Idealization
    Conferences and Volumes: [2012] Philosophy of Science Assoc. 23rd Biennial Mtg (San Diego, CA) > PSA 2012 Contributed Papers
    Depositing User: Tarja Tellervo Knuuttila
    Date Deposited: 15 May 2013 17:06
    Last Modified: 15 May 2013 17:06
    Item ID: 9764
    URI: http://philsci-archive.pitt.edu/id/eprint/9764

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