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Crystallizing Techniques: Sample Preparations, Technical Knowledge, and the Characterization of Blood Crystals, 1840-1909

Matthiessen, Dana (2024) Crystallizing Techniques: Sample Preparations, Technical Knowledge, and the Characterization of Blood Crystals, 1840-1909. [Preprint]

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Abstract

Sample preparation is the process of altering a naturally occurring object into a representative form that is amenable to scientific inquiry. Preparation is an important preliminary to data collection, ubiquitous in the life sciences and elsewhere, yet relatively neglected in historical and philosophical literature. This paper presents a detailed historical case study involving the preparation and study of blood crystals in the nineteenth century. The case is used to highlight significant features of preparation, which aid our understanding of the epistemology of sciences in which preparations play an important role. First, it shows the role of technical knowledge in efforts to characterize a scientific phenomenon or object of interest. Especially in early stages of characterization, scientists improve their understanding of what they are preparing by better understanding their preparation procedures. Second, this case contributes to recent views of characterization as a relatively autonomous domain of scientific activity. It shows how preparation functions as a site for integrating different experimental methods, and the difficulties that ensue. In light of these considerations, the case shows how characterization is capable of shaping or constraining explanatory pursuits as much as it is guided by them.


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Item Type: Preprint
Creators:
CreatorsEmailORCID
Matthiessen, Danadam228@pitt.edu
Keywords: Sample Preparation, Experimentation, Characterization, Biochemistry
Subjects: General Issues > Data
Specific Sciences > Biology
Specific Sciences > Chemistry
General Issues > Experimentation
General Issues > Technology
Depositing User: Dana Matthiessen
Date Deposited: 22 Oct 2024 12:03
Last Modified: 22 Oct 2024 12:03
Item ID: 24092
Subjects: General Issues > Data
Specific Sciences > Biology
Specific Sciences > Chemistry
General Issues > Experimentation
General Issues > Technology
Date: 21 October 2024
URI: https://philsci-archive.pitt.edu/id/eprint/24092

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