Gaillard, Maxence and Pence, Charles H. and Botbol-Baum, Mylène (2025) Organoid Ethical Typology: varieties of three-dimensional stem cell constructs and the many issues they raise in bioethics. Biology of the Cell, 117 (1). e2400093.

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Abstract

The advancement of and prospects for stem cell research raise a number of specific ethical issues. While navigating the ethical landscape of stem cell research is often challenging for biology researchers and biotechnology innovators, it is also difficult for the public and other persons of concern (from ethicists to policy-makers) to grasp the technicalities of a burgeoning field that develops in many directions. Organoids are one of these new biotechnological constructs that are currently eliciting a rich debate in bioethics. In this guide, we argue that different types of organoids have different emerging properties with different ethical implications. Going from general properties to particular ones, we propose a typology of organoid technology and other associated biotechnology from a philosophical and ethical perspective. We point to relevant ethical issues and try to convey the sense of uncertainty peculiar to ongoing research and emerging technological objects.

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Item Type:	Published Article or Volume
Creators:	Creators Email ORCID Gaillard, Maxence Pence, Charles H. charles@charlespence.net 0000-0002-6836-6047 Botbol-Baum, Mylène
Keywords:	bioethics, biotechnology, ethics of science and medicine, organoids, stem cells
Subjects:	Specific Sciences > Biology > Molecular Biology/Genetics Specific Sciences > Medicine > Biomedical Ethics General Issues > Ethical Issues
Depositing User:	Charles H. Pence
Date Deposited:	01 Feb 2025 14:10
Last Modified:	01 Feb 2025 14:10
Item ID:	24664
Journal or Publication Title:	Biology of the Cell
Publisher:	John Wiley & Sons
Official URL:	https://onlinelibrary.wiley.com/doi/full/10.1111/b...
DOI or Unique Handle:	10.1111/boc.202400093
Subjects:	Specific Sciences > Biology > Molecular Biology/Genetics Specific Sciences > Medicine > Biomedical Ethics General Issues > Ethical Issues
Date:	24 January 2025
Page Range:	e2400093
Volume:	117
Number:	1
URI:	https://philsci-archive.pitt.edu/id/eprint/24664

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