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Validating Animal Models

Atanasova, Nina (2015) Validating Animal Models. THEORIA. An International Journal for Theory, History and Foundations of Science, 30 (2). pp. 163-181. ISSN 2171-679X

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Abstract

This paper responds to a recent challenge for the validity of extrapolation of neurobiological knowledge from laboratory animals to humans. According to this challenge, experimental neurobiology, and thus neuroscience, is in a state of crisis because the knowledge produced in different laboratories hardly generalizes from one laboratory to another. Presumably, this is so because neurobiological laboratories use simplified animal models of human conditions that differ across laboratories. By contrast, I argue that maintaining a multiplicity of experimental protocols and simple models is well justified. It fosters rather than precludes the validity of extrapolation of neurobiological knowledge. The discipline is thriving.


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Item Type: Published Article or Volume
Creators:
CreatorsEmailORCID
Atanasova, Ninanina.atanasova@utoledo.edu
Additional Information: ISSN: 0495-4548 (print)
Keywords: animal models; calibration; validity; reliability; experimental neurobiology
Subjects: General Issues > Experimentation
General Issues > Models and Idealization
Specific Sciences > Biology > Neuroscience
Depositing User: Unnamed user with email theoria@ehu.es
Date Deposited: 07 Jun 2016 13:10
Last Modified: 07 Jun 2016 13:10
Item ID: 12145
Journal or Publication Title: THEORIA. An International Journal for Theory, History and Foundations of Science
Publisher: Euskal Herriko Unibertsitatea / Universidad del País Vasco
Official URL: http://www.ehu.eus/ojs/index.php/THEORIA/article/v...
DOI or Unique Handle: 10.1387/theoria.12761
Subjects: General Issues > Experimentation
General Issues > Models and Idealization
Specific Sciences > Biology > Neuroscience
Date: May 2015
Page Range: pp. 163-181
Volume: 30
Number: 2
ISSN: 2171-679X
URI: http://philsci-archive.pitt.edu/id/eprint/12145

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