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The machine-like repair of aging. Disentangling the key assumptions of the SENS agenda

García-Barranquero, Pablo and Bertolaso, Marta (2022) The machine-like repair of aging. Disentangling the key assumptions of the SENS agenda. THEORIA. An International Journal for Theory, History and Foundations of Science, 37 (3). pp. 379-394. ISSN 2171-679X

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Abstract

The possibility of curing aging is currently generating hopes and concerns among entrepreneurs, experts, and the general public. This article aims to clarify some of the key assumptions of the Strategies for Engineered Negligible Senescence agenda, one of the most prominent paradigms for rejuvenation. To do this, we present the three fundamental claims of this research program: (1) aging can be repaired; (2) rejuvenation is possible through the reversal of all molecular damage; (3) and the human organism is a sophisticated machine. Secondly, we argue that this agenda fits with a machine conception of the organism (described by Daniel Nicholson); we show that, if aging is understood from this philosophical approach, there is an internal confusion in the research program between what is repair and what is rejuvenation. Finally, we state that this theoretical viewpoint connects with scientific criticism and reinforces the idea that there are limits to the aspirations to live indefinitely young.


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Item Type: Published Article or Volume
Creators:
CreatorsEmailORCID
García-Barranquero, Pablopablogarcia@uma.es0000-0001-6472-5703
Bertolaso, Martam.bertolaso@unicampus.it0000-0003-2241-7029
Additional Information: ISSN: 0495-4548 (print)
Keywords: aging, machine, repair, rejuvenation, SENS
Subjects: Specific Sciences > Engineering
Specific Sciences > Medicine > Health and Disease
General Issues > Science and Society
Depositing User: Unnamed user with email theoria@ehu.es
Date Deposited: 06 Feb 2023 16:48
Last Modified: 06 Feb 2023 16:48
Item ID: 21732
Journal or Publication Title: THEORIA. An International Journal for Theory, History and Foundations of Science
Publisher: Euskal Herriko Unibertsitatea / Universidad del País Vasco
Official URL: https://ojs.ehu.eus/index.php/THEORIA/article/view...
DOI or Unique Handle: 10.1387/theoria.23544
Subjects: Specific Sciences > Engineering
Specific Sciences > Medicine > Health and Disease
General Issues > Science and Society
Date: September 2022
Page Range: pp. 379-394
Volume: 37
Number: 3
ISSN: 2171-679X
URI: https://philsci-archive.pitt.edu/id/eprint/21732

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