Robins, Sarah (2018) Memory and Optogenetic Intervention: Separating the Engram from the Ecphory. [Preprint]
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Abstract
Optogenetics makes possible the control of neural activity with light. In this paper, I explore how the development of this experimental tool has brought about methodological and theoretical advances in the neurobiological study of memory. I begin with Semon's (1921) distinction between the engram and the ecphory, explaining how these concepts present a methodological challenge to investigating memory. Optogenetics provides a way to intervene into the engram without the ecphory that, in turn, opens up new means for testing theories of memory error. I focus on a series of experiments where optogenetics is used to study false memory and forgetting.
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| Item Type: | Preprint | ||||||
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| Keywords: | memory, engram, optogenetics, Richard Semon | ||||||
| Subjects: | General Issues > Experimentation General Issues > Theory Change |
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| Depositing User: | Dr. Sarah Robins | ||||||
| Date Deposited: | 01 Feb 2018 22:27 | ||||||
| Last Modified: | 01 Feb 2018 22:27 | ||||||
| Item ID: | 14341 | ||||||
| Subjects: | General Issues > Experimentation General Issues > Theory Change |
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| Date: | 30 January 2018 | ||||||
| URI: | https://philsci-archive.pitt.edu/id/eprint/14341 |
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