Rondeau, Elena and Larmonier, Nicolas and Pradeu, Thomas and Bikfalvi, Andreas
(2019)
Philosophy of Biology: Characterizing causality in cancer.
eLife, 8.
e53755.
Abstract
Philosophers have explored the concept of causality for centuries. Here we argue that ideas about causality from philosophy can help scientists to better understand how cancerous tumors grow and spread in the body. After outlining six characteristics of causality that are relevant to cancer, we emphasize the importance of feedback loops and interactions between tumor-cell-intrinsic and tumor-cell-extrinsic factors for explaining the formation and dissemination of tumors.
Item Type: |
Article
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Creators: |
Creators | Email | ORCID |
---|
Rondeau, Elena | | | Larmonier, Nicolas | | | Pradeu, Thomas | | | Bikfalvi, Andreas | | |
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Keywords: |
metastasis, carcinogenesis, causality, philosophy of biology |
Depositing User: |
Thomas Pradeu
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Date Deposited: |
16 Oct 2020 14:10 |
Last Modified: |
16 Oct 2020 14:10 |
Item ID: |
18234 |
Journal or Publication Title: |
eLife |
Official URL: |
https://doi.org/10.7554/eLife.53755 |
Date: |
November 2019 |
Page Range: |
e53755 |
Volume: |
8 |
URI: |
https://philsci-archive.pitt.edu/id/eprint/18234 |
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