Laurent, Paôline and Jolivel, Valérie and Manicki, Pauline and Chiu, Lynn and Contin-Bordes, Cécile and Truchetet, Marie-Elise and Pradeu, Thomas (2017) Immune-Mediated Repair: A Matter of Plasticity. Frontiers in Immunology, 8. ISSN 1664-3224

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Abstract

Though the immune system is generally defined as a system of defense, it is increasingly
recognized that the immune system also plays a crucial role in tissue repair and its potential dysregulations. In this review, we explore how distinct immune cell types are involved
in tissue repair and how they interact in a process that is tightly regulated both spatially
and temporally. We insist on the concept of immune cell plasticity which, in recent years,
has proved fundamental for the success/understanding of the repair process. Overall,
the perspective presented here suggests that the immune system plays a central role in
the physiological robustness of the organism, and that cell plasticity contributes to the
realization of this robustness.

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Item Type:	Published Article or Volume
Creators:	Creators Email ORCID Laurent, Paôline Jolivel, Valérie Manicki, Pauline Chiu, Lynn Contin-Bordes, Cécile Truchetet, Marie-Elise Pradeu, Thomas
Depositing User:	Thomas Pradeu
Date Deposited:	18 Oct 2020 02:46
Last Modified:	18 Oct 2020 02:46
Item ID:	18262
Journal or Publication Title:	Frontiers in Immunology
Official URL:	http://doi.org/10.3389/fimmu.2017.00454
DOI or Unique Handle:	10.3389/fimmu.2017.00454
Date:	2017
Volume:	8
ISSN:	1664-3224
URI:	https://philsci-archive.pitt.edu/id/eprint/18262

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