Casini, Lorenzo and Landes, Juergen (2024) Conflict of Interest and the Principle of Total Evidence. [Preprint]
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Abstract
Many clinical trials suffer from conflicts of interest, such as sponsorship by pharmaceutical companies. “Meta-research” evidence suggests that conflicts of interest raise the probability of biased estimates. And yet, the very same trials are prima facie more reliable than trials not subject conflict of interest, in virtue of their better design. How
should one deal with this seemingly conflicting information? In this paper, we propose a Bayesian model to elucidate the bearing of meta-research evidence on the hypothesis of interest.
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| Item Type: | Preprint | |||||||||
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| Additional Information: | In Piazza, M, Tesi, M. and Vigiani, P (eds), Proceedings of the Workshop Reasoning with Imperfect Information in Social Settings, Edizioni della Normale. | |||||||||
| Keywords: | conflict of interest; bias; randomized trials; Bayesian epistemology | |||||||||
| Subjects: | General Issues > Confirmation/Induction General Issues > Evidence Specific Sciences > Medicine |
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| Depositing User: | Dr. Lorenzo Casini | |||||||||
| Date Deposited: | 08 Feb 2024 02:11 | |||||||||
| Last Modified: | 08 Feb 2024 02:11 | |||||||||
| Item ID: | 23057 | |||||||||
| Subjects: | General Issues > Confirmation/Induction General Issues > Evidence Specific Sciences > Medicine |
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| Date: | 31 January 2024 | |||||||||
| URI: | https://philsci-archive.pitt.edu/id/eprint/23057 |
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