Lean, Oliver M (2019) Binding Specificity and Causal Selection in Drug Design. [Preprint]
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Abstract
Binding specificity is a centrally important concept in molecular biology, yet it has received little philosophical attention. Here I aim to remedy this by analyzing binding specificity as a causal property. I focus on the concept’s role in drug design, where it is highly prized and hence directly studied: From a causal perspective, understanding why binding specificity is a valuable property of drugs contributes to an understanding of causal selectionーof how and why scientists distinguish between causes, not just causes from non-causes. In particular, the specificity of drugs is precisely what underwrites their value as experimental interventions on biological processes.
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| Item Type: | Preprint | ||||||
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| Additional Information: | Forthcoming in "Philosophy of Science" | ||||||
| Keywords: | causation; causality; causal selection; molecular biology; specificity; drug design; intervention | ||||||
| Subjects: | Specific Sciences > Biology > Molecular Biology/Genetics General Issues > Causation General Issues > Evidence General Issues > Technology |
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| Depositing User: | Dr. Oliver Lean | ||||||
| Date Deposited: | 07 Aug 2019 13:44 | ||||||
| Last Modified: | 07 Aug 2019 13:44 | ||||||
| Item ID: | 16314 | ||||||
| Subjects: | Specific Sciences > Biology > Molecular Biology/Genetics General Issues > Causation General Issues > Evidence General Issues > Technology |
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| Date: | 2019 | ||||||
| URI: | https://philsci-archive.pitt.edu/id/eprint/16314 |
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Binding Specificity and Causal Selection in Drug Design. (deposited 05 Jul 2019 03:16)
- Binding Specificity and Causal Selection in Drug Design. (deposited 07 Aug 2019 13:44) [Currently Displayed]
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