Pradeu, Thomas and Cooper, Edwin L. (2012) The danger theory: 20 years later. Frontiers in Immunology, 3. ISSN 1664-3224
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Official URL: http://doi.org/10.3389/fimmu.2012.00287
Abstract
The self–non-self theory has dominated immunology since the 1950s. In the 1990s, Matzinger and her colleagues suggested a new, competing theory, called the “danger theory.” This theory has provoked mixed acclaim: enthusiasm and criticism. Here we assess the danger theory vis-à-vis recent experimental data on innate immunity, transplantation, cancers and tolerance to foreign entities, and try to elucidate more clearly whether danger is well defined.
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| Item Type: | Published Article or Volume | |||||||||
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| Depositing User: | Thomas Pradeu | |||||||||
| Date Deposited: | 18 Oct 2020 02:34 | |||||||||
| Last Modified: | 18 Oct 2020 02:34 | |||||||||
| Item ID: | 18244 | |||||||||
| Journal or Publication Title: | Frontiers in Immunology | |||||||||
| Official URL: | http://doi.org/10.3389/fimmu.2012.00287 | |||||||||
| DOI or Unique Handle: | 10.3389/fimmu.2012.00287 | |||||||||
| Date: | 2012 | |||||||||
| Volume: | 3 | |||||||||
| ISSN: | 1664-3224 | |||||||||
| URI: | https://philsci-archive.pitt.edu/id/eprint/18244 |
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