Pradeu, Thomas and Vivier, Eric (2016) The discontinuity theory of immunity. Science Immunology, 1 (1). aag0479-aag0479. ISSN 2470-9468
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Official URL: http://doi.org/10.1126/sciimmunol.aag0479
Abstract
Similar to many other biological systems, the immune system can be seen as a change-detection system. According to the discontinuity theory of immunity, the immune system responds to sudden changes in antigenic stimulation and is rendered tolerant by slow or continuous stimulation. This basic principle, which is supported by recent data on immune checkpoints in viral infections, cancers, and allergies, can be seen as a unifying framework for diverse immune responses.
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| Item Type: | Published Article or Volume | |||||||||
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| Depositing User: | Thomas Pradeu | |||||||||
| Date Deposited: | 18 Oct 2020 02:37 | |||||||||
| Last Modified: | 18 Oct 2020 02:37 | |||||||||
| Item ID: | 18248 | |||||||||
| Journal or Publication Title: | Science Immunology | |||||||||
| Official URL: | http://doi.org/10.1126/sciimmunol.aag0479 | |||||||||
| DOI or Unique Handle: | 10.1126/sciimmunol.aag0479 | |||||||||
| Date: | 2016 | |||||||||
| Page Range: | aag0479-aag0479 | |||||||||
| Volume: | 1 | |||||||||
| Number: | 1 | |||||||||
| ISSN: | 2470-9468 | |||||||||
| URI: | https://philsci-archive.pitt.edu/id/eprint/18248 |
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