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When remediating one artifact results in another: control, confounders, and correction

Colaço, David (2024) When remediating one artifact results in another: control, confounders, and correction. History and Philosophy of the Life Sciences, 46 (5).

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Abstract

Scientists aim to remediate artifacts in their experimental datasets. However, the remediation of one artifact can result in another. Why might this happen, and what does this consequence tell us about how we should account for artifacts and their control? In this paper, I explore a case in functional neuroimaging where remediation appears to have caused this problem. I argue that remediation amounts to a change to an experimental arrangement. These changes need not be surgical, and the arrangement need not satisfy the criterion of causal modularity. Thus, remediation can affect more than just the factor responsible for the artifact. However, if researchers can determine the consequences of their remediation, they can make adjustments that control for the present artifact as well as for previously controlled ones. Current philosophical accounts of artifacts and the factors responsible for them cannot adequately address this issue, as they do not account for what is needed for artifact remediation (and specifically correction). I support my argument by paralleling it with ongoing concerns regarding the transparency of complex computational systems, as near future remediation across the experimental life sciences will likely make greater use of AI tools to correct for artifacts.


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Item Type: Published Article or Volume
Creators:
CreatorsEmailORCID
Colaço, David
Additional Information: This article is licensed under a Creative Commons Attribution 4.0 International License.
Keywords: experiment; artifact; experimental control; confounder
Subjects: Specific Sciences > Artificial Intelligence
General Issues > Experimentation
Specific Sciences > Neuroscience
Depositing User: Dr. David Colaço
Date Deposited: 07 Feb 2024 01:01
Last Modified: 07 Feb 2024 01:01
Item ID: 23055
Journal or Publication Title: History and Philosophy of the Life Sciences
Publisher: Springer
Official URL: https://link.springer.com/article/10.1007/s40656-0...
DOI or Unique Handle: https://doi.org/10.1007/s40656-023-00606-2
Subjects: Specific Sciences > Artificial Intelligence
General Issues > Experimentation
Specific Sciences > Neuroscience
Date: 2024
Volume: 46
Number: 5
URI: https://philsci-archive.pitt.edu/id/eprint/23055

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