Lohse, Simon (2024) Questionable Research Practices and the Reproducibility Crisis in Animal-Based Biomedicine: A New Perspective. [Preprint]

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Abstract

I discuss reproducibility issues in animal-based research in biomedicine and scrutinize the notion that the causes of non-reproducible results are the same as in other disciplines. I argue that there are aspects characteristic of animal experimentation that are important for analysing reproducibility problems but have not yet been discussed in this context. Using an approach that integrates epistemological and ethical questions, I explore these aspects and show that the prevalent focus on questionable research practices and methodological reforms falls short in understanding and managing key challenges to reproducibility in animal-based biomedicine.

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Item Type:	Preprint
Creators:	Creators Email ORCID Lohse, Simon simon.lohse@ru.nl 0000-0002-4119-1929
Keywords:	Replication crisis; animal experimentation; standardisation; 3R principle; philosophy of science in practice
Subjects:	Specific Sciences > Biology Specific Sciences > Medicine
Depositing User:	Dr. S. Lohse
Date Deposited:	21 Oct 2024 15:18
Last Modified:	21 Oct 2024 15:18
Item ID:	24086
Subjects:	Specific Sciences > Biology Specific Sciences > Medicine
Date:	2024
URI:	https://philsci-archive.pitt.edu/id/eprint/24086

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