Daly, Timothy (2025) The Meanings of Alzheimer’s Disease. Philosophy of Medicine, 6 (1). pp. 1-11. ISSN 2692-3963
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Abstract
Alzheimer’s disease emerged around the 1900s as a rare disease that became synonymous with common dementia by the 1980s. In the 2010s, in vivo biomarkers of Alzheimer’s pathophysiology then led researchers to emphasize the presymptomatic biology of Alzheimer’s biomarkers, thus decentering dementia. Three consensus definitions were elaborated around biomarkers, and were rearticulated in 2024: biomarker-determined Alzheimer’s disease; biomarker-informed “clinical-biological” Alzheimer’s disease; and biomarker-independent, “all-cause” dementia. I consider their differences to hinge on the questionable legitimacy of the Alzheimer “biomarkerization” of aging. I encourage a focus on the actionable concept of brain health beyond Alzheimer’s to motivate equitable health promotion.
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| Item Type: | Published Article or Volume | ||||||
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| Keywords: | Alzheimer's disease Concepts of health and disease Public health | ||||||
| Subjects: | Specific Sciences > Medicine > Health and Disease Specific Sciences > Medicine |
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| Depositing User: | Professor Alex Broadbent | ||||||
| Date Deposited: | 12 May 2025 12:40 | ||||||
| Last Modified: | 12 May 2025 12:40 | ||||||
| Item ID: | 25284 | ||||||
| Journal or Publication Title: | Philosophy of Medicine | ||||||
| Publisher: | University Library System, University of Pittsburgh | ||||||
| Official URL: | https://philmed.pitt.edu/philmed/article/view/251 | ||||||
| DOI or Unique Handle: | 10.5195/pom.2025.251 | ||||||
| Subjects: | Specific Sciences > Medicine > Health and Disease Specific Sciences > Medicine |
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| Date: | 9 May 2025 | ||||||
| Page Range: | pp. 1-11 | ||||||
| Volume: | 6 | ||||||
| Number: | 1 | ||||||
| ISSN: | 2692-3963 | ||||||
| URI: | https://philsci-archive.pitt.edu/id/eprint/25284 |
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