Fagan, Melinda B. (2012) The stem cell uncertainty principle. In: UNSPECIFIED.
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Abstract
Stem cells are defined by capacities for both self-renewal and differentiation. Many different entities satisfy this working definition. Explicating the stem cell concept reveals it to be relational and relative, requiring contextualization by a cell lineage, organismal source, cell environments, and traits of interest. Not only are stem cell capacities relative to an experimental context; the stem cell concept imposes evidential constraints on the interpretation of experimental results. In consequence, claims about stem cell capacities are inherently uncertain. I discuss the implications of this result for progress in stem cell research and its public understanding.
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Item Type: | Conference or Workshop Item (UNSPECIFIED) | ||||||
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Keywords: | Experiment, Models, Stem cells, Technology, Uncertainty | ||||||
Subjects: | Specific Sciences > Biology > Developmental Biology Specific Sciences > Biology > Molecular Biology/Genetics General Issues > Experimentation |
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Depositing User: | Melinda Fagan | ||||||
Date Deposited: | 02 Jul 2012 16:23 | ||||||
Last Modified: | 02 Jul 2012 16:23 | ||||||
Item ID: | 9198 | ||||||
Subjects: | Specific Sciences > Biology > Developmental Biology Specific Sciences > Biology > Molecular Biology/Genetics General Issues > Experimentation |
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Date: | 1 July 2012 | ||||||
URI: | https://philsci-archive.pitt.edu/id/eprint/9198 |
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