Ratti, Emanuele and D'Agostino, Giuseppe (2025) Beyond 'Trapped Pets' and 'Red Buttons': Bioinformatics as an Experimental Discipline. [Preprint]
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Abstract
The past few years have witnessed a growth in the interest on the historical and philosophical dimensions of bioinformatics as a discipline. Despite the importance of bioinformatics in addressing the issues raised by the growing amount of biological data, data management is often seen as all it has to offer to biology. However, the emphasis on data management may come at the expense of understanding how bioinformatics generates genuine biological knowledge beyond its instrumental value for bench biologists. Some authors have moved the first steps beyond data management, and towards the characterization of bioinformatics as a unique epistemic endeavor, by stressing how its experimental practices can be conducive to biological knowledge. In this article, we build upon these attempts, and by using a detailed case study from the field of single cell transcriptomics (i.e., RNA velocity), we provide a fully-fledged characterization of bioinformatics as an experimental discipline.
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| Item Type: | Preprint | |||||||||
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| Additional Information: | Accepted for publication in 'Perspectives on Science' | |||||||||
| Keywords: | bioinformatics big data biology experiments molecular biology | |||||||||
| Subjects: | Specific Sciences > Biology > Molecular Biology/Genetics Specific Sciences > Computer Science Specific Sciences > Artificial Intelligence General Issues > Experimentation General Issues > Technology |
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| Depositing User: | Dr Emanuele Ratti | |||||||||
| Date Deposited: | 24 Jan 2025 14:40 | |||||||||
| Last Modified: | 24 Jan 2025 14:40 | |||||||||
| Item ID: | 24609 | |||||||||
| Subjects: | Specific Sciences > Biology > Molecular Biology/Genetics Specific Sciences > Computer Science Specific Sciences > Artificial Intelligence General Issues > Experimentation General Issues > Technology |
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| Date: | 2025 | |||||||||
| URI: | https://philsci-archive.pitt.edu/id/eprint/24609 |
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